Boysenberries and Labradoodles are manufactured hybrids. Before someone got the wild hair to combine a blackberry, raspberry, and loganberry we did not have the tasty fruit—not to mention how before that fateful canine honeymoon, lovers of the odd combo of a Labrador Retriever and a Poodle would be without their curly haired pups.
Hybrids in audio are so common these days as to become standard fare: vacuum tubes and MOSFETS, JFETS and BJTS, SMPS power supplies and analog circuits.
In fact, let's pull back from the uber technical to the more practical. Think of a vacuum tube preamplifier connected to a solid state power amplifier, or a cone subwoofer augmenting a planar or electrostatic loudspeaker.
Kennel clubs might prize the pure bred, but when it comes to high-end audio, the hybrid makes magic.